Mouse model of intestinal tumorigenesis

NIAID Data Ecosystem2026-03-10 收录

肠道肿瘤发生

自噬抑制

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP058961 数据链接链接失效反馈

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资源简介：

This project aims at studying the importance of autophagy inhibition within the epithelium in the prevention of intestinal cancer development and progression

创建时间：

2017-09-17

Cited1 Deficiency Suppresses Intestinal Tumorigenesis

肠道肿瘤发生

基因调控

Conditional deletion of Apc in the murine intestine alters crypt-villus architecture and function. This process is accompanied by multiple changes in gene expression, including upregulation of Cited1,

NIAID Data Ecosystem100

Identification of aging-associated gene expression signatures that precede intestinal tumorigenesis [mouse]. Mus musculus

肠道肿瘤发生

衰老基因表达

Aging-associated gene expression alterations have been implicated in various cancers including colorectal cancer. We examined aging-associated gene expression signatures that precede intestinal tumori

NIAID Data Ecosystem50

Autophagy Inhibition via Targeting of PIKfyve Potentiates Immune Checkpoint Blockade in Prostate Cancer Therapy

癌症免疫治疗

自噬抑制

To understand the tumor microenvironment changes in terms of transcriptome upon PIKfyve inhibition by small molecule ESK981 and the immune checkpoint inhibitor anti-PD-1 in Myc-CaP syngeneic mouse mod

NIAID Data Ecosystem40

Supplementary Material for: Ulinastatin improves renal microcirculation by protecting endothelial cells and inhibiting autophagy in a septic rat model

肾脏研究

自噬抑制

Introduction: Increased permeability of the renal capillaries is a common consequence of sepsis-associated acute kidney injury. Vascular endothelial (VE)-cadherin is a strictly endothelial-specific ad

DataCite Commons2022-03-09 更新80

Identification of compound CA-5f as a novel late-stage autophagy inhibitor with potent anti-tumor effect against non-small cell lung cancer

自噬抑制

抗肿瘤研究

Currently, particular focus is placed on the implication of autophagy in a variety of human diseases, including cancer. Discovery of small-molecule modulators of autophagy as well as their potential u

DataCite Commons2024-02-13 更新50

Mouse model of intestinal tumorigenesis

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