five

SOCS3 deficiency blocked autophagy-dependent myeloid differentiation of early-stage myeloid-derived suppressor cells via the miR-155/C/EBPß/Wnt axis

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https://www.ncbi.nlm.nih.gov/sra/SRP229106
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To explore which pathways participated in dysfunctional eMDSC differentiation, we performed RNA sequencing on Gr-1 cells, eMDSCsfl/fl and eMDSCsKO to screen for potential candidates that might participate in the SOCS3-deficiency-induced differentiation arrest in eMDSCs. Overall design: mRNA profiles of Gr_1, WT and SOCS3-/- mice were generated by deep sequencing, in triplicate, using Illumina.
创建时间:
2022-11-11
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