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Modeling Fanconi Anemia pathogenesis and therapeutics using integration-free patient iPSCs [RNA-seq]

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NIAID Data Ecosystem2026-03-10 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP042119
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资源简介:
We compared the epigenetic status of the mutant and disease-free iPSCs at the whole genome level. Whole epigenome profiling based on trimethylated H3K4 (H3K4me3) showed concordant epigenetic remodeling in the two corrected clones when compared with two mutant iPSC clones. Overall design: Examination of genome-wide gene expression in Fanconi anemia patient iPSCs before and after gene correction
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2017-12-23
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