Animal characteristics and echocardiographic measurements 3 weeks after sham operation or aortic banding.
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Sham, sham operated group; AB, aorta banding group; WT, wild-type mice; CCR7−/−, CCR7 knock-out mice; BW, body weight; TL, tibia- length; LVW/TL, left ventricular weight normalized to TL; RVW/TL, right ventricular weight normalized to TL; LW/TL, lung weight normalized to TL; Echo-MM, M-mode echocardiography; IVSd/TL, interventricular septum thickness in diastole normalized to TL; LVDd/TL, left ventricular diameter in diastole normalized to TL; PWd/TL, posterior wall thickness in diastole normalized to TL; LVFS, left ventricular fractional shortening; LAD/TL, left atrial diameter normalized to TL; HR, heart rate; Mit Vmax, peak mitral flow; Mit dec, mitral deceleration velocity; AB Vmax, peak flow through aortic banding; LVOT Vmax, peak left ventricular outflow tract flow; VTI, velocity time integral; CO, cardiac output; *p<0.05 vs sham in respective genotype group and †p<0.05 vs Wt in same group. Values are means ± SEM. Animal characteristics and echocardiographic measurements 3 weeks after sham operation or aortic banding.



