5-year cumulative mortality rate, incident rates of acute CVD and recurrent stroke, HR and 95% CI (non-LI vs LI).

*Adjusted for age, gender, hypertension, diabetes, dislipidemia, cardiac disease, overweight or obesity, smoking status, drinking status, BI index, depression symptoms, aspirin treatment. LI, Lacunar Infarction; non-LI, non-lacunar infarction, including thrombotic brain infarction and cardioembolic stroke; Acute CVD, acute cardiovascular diseases including acute myocardial infarction, sudden death and recurrent stroke; Recurrent stroke including ischemic stroke, intracerebral hemorrhage and subarachnoid hemorrhage; HR, Hazard ratio; CI, Confidence interval.