Drought induced transcriptomic changes in tobacco

The drought stress is one of key adverse environmental factors limiting plant growth and development, even threating global crop productivity in many arid and semi-arid regions. Drought stress usually causes huge economic losses for tobacco industries. Understanding how plants respond and adapt to the drought stress helps generate engineered plants with enhanced drought resistance. In this study, integrative analyses of multiple time point-related transcriptome and metabolome generated from K326 and its derived mutant 28 (M28) with contrasting drought tolerance. We found that dramatic changes of gene expression profiles between M28 and K326 before and after drought treatment. we conducted transcriptional analyses using K326 and its derived mutant 28 (M28) with contrasting drought tolerance. Through integration of RNA-seq and construction of gene regulatory networks, we revealed that some key genes directly or indirectly regulate in drought responses.