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Table S2 from Impact of the Anticancer Drug NT157 on Tyrosine Kinase Signaling Networks

Figshare2018-05-01 更新2026-04-28 收录

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https://figshare.com/articles/dataset/Table_S2_from_Impact_of_the_Anticancer_Drug_NT157_on_Tyrosine_Kinase_Signaling_Networks/22505359 数据链接链接失效反馈

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Summary of kinase panel used for testing of NT157 activity.

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创建时间：

2018-05-01

T细胞免疫调节

药物机制研究

To determine the effect of DSF on T cell activation ,we treated T cells with DSF and analyzed their functions. Comparative gene expression profiling analysis of RNA-seq for T cells after treated with

NIAID Data Ecosystem60

Gene expression signatures in oridonin-treated WT and R878H hematopoietic stem cells. Gene expression signatures in oridonin-treated WT and R878H hematopoietic stem cells

药物机制研究

干细胞生物学

Analysis of WT-Ctl v.s. WT-Ori and R878H-Ctl v.s. R878H-Ori hematopoietic stem cell (lineage-, c-kit+ Sca-1+ CD150+, CD34-). The four population of hematopoietic stem cell (HSC) were purified from the

NIAID Data Ecosystem60

C57bl/6 liver Transcriptome. Mus musculus

疾病转录组学

药物机制研究

there are few reports on rhein effects on liver diseases. Therefore, this study aims to investigate these effects and underlying mechanisms.

NIAID Data Ecosystem50

Top three gene ontology biological processes resulting from the analysis of differential regulated genes between antioxidant drugs and the respective solvent controls.

基因本体富集分析

药物机制研究

This analysis was performed using the DAVID program (see MM). Count indicates the number of genes belonging to the indicated gene ontology biological processes that we found regulated by a factor 2; %

NIAID Data Ecosystem60

CDK4/6 inhibitors induce repication stress to cause long-term cell cycle withdrawal

细胞周期调控

药物机制研究

CDK4/6 inhibitors arrest the cell cycle in G1-phase. They are licenced to treat breast cancer and are also undergoing clinical trials against a range of other tumour types. To facilitate these efforts

NIAID Data Ecosystem60

Table S2 from Impact of the Anticancer Drug NT157 on Tyrosine Kinase Signaling Networks

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