Ectopic histone modification in extra-embryonic tissues influence implantation and placenta development of IVF embryos [ChIP-Seq 2]
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https://www.ncbi.nlm.nih.gov/sra/SRP362483
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To further investigate the relationship between abnormal accumulation of H3K4me3 modification and abnormal embryo development. We injected Kdm5b siRNA, which is an H3K4me3 eraser, at the zygote (PN3-PN4) stage of NM embryos and then examined the H3K4me3 modification of extraembryonic ectoderm at E7.5. Overall design: Examination H3K4me3 modification of extraembryonic ectoderm with sikdm5b or water.
创建时间：
2022-05-27
