Cryo-EM structure of the pre-mRNA-loaded DEAH-box ATPase/helicase Prp2 in complex with Spp2

NIAID Data Ecosystem2026-05-01 收录

剪接体解旋酶复合物结构

pre-mRNA剪接

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Cryo-EM structure of the pre-mRNA-loaded DEAH-box ATPase/helicase Prp2 in complex with Spp2

创建时间：

2024-03-27

Mus musculus with altered pre-mRNA processing

pre-mRNA剪接

基因敲除表型分析

mRNA processing is an essential step of gene expression; its malfunction can lead to different degrees of physiological disorder, from subclinical disease to death. DIDO3, the larger protein encoded b

NIAID Data Ecosystem60

Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 50

剪接体RNA解旋酶结构

pre-mRNA剪接

Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 50 Descriptor: Pre-mRNA-processing-splicing factor 8, U5 small nuclear ribonucleoprotein 200 kDa helicase, phenylsulfonylcar

Protein Data Bank Japan2024-02-07 更新20

RNA-seq analysis of the budding yeast ctk1? and rad6? strains and prp45(1-169) ctk1? and prp45(1-169) rad6? double mutant strains

转录调控机制

pre-mRNA剪接

Prp45 is a budding yeast NineTeen-Complex associated factor, which plays a role in pre-mRNA splicing. Because its human ortholog, SNW1/SKIP, is known to functionally and physically interact with facto

NIAID Data Ecosystem10

A Gene Expression and Pre-mRNA Splicing Signature That Marks the Adenoma-Adenocarcinoma Progression in Colorectal Cancer

结直肠癌分子标志物

pre-mRNA剪接

It is widely accepted that most colorectal cancers (CRCs) arise from colorectal adenomas (CRAs), but transcriptomic data characterizing the progression from colorectal normal mucosa to adenoma, and th

NIAID Data Ecosystem50

Arabidopsis MOS4-associated complex promotes microRNA biogenesis and pre-mRNA splicing [ncRNA-seq]. Arabidopsis thaliana

microRNA生物合成

pre-mRNA剪接

The evolutionarily conserved, putative RNA helicase MAC7 exists in both animals and plants. The human MAC7 homolog, Aquarius, is part of the spliceosome and plays a role in pre-mRNA splicing in vitro.

NIAID Data Ecosystem20

Cryo-EM structure of the pre-mRNA-loaded DEAH-box ATPase/helicase Prp2 in complex with Spp2

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