Duplex sequencing of mtDNA from rhesus macaque somatic tissues (liver, skeletal muscle, and heart), and single oocytes was performed to study the effect of aging on mtDNA substitution frequencies. Mac
This file contains part of the independent variants set we have collected from ClinVar and gnomAD v2. Particularly, this file contains only benign variants subset.
Somatic stem cells mediate tissue maintenance for the lifetime of an organism. Despite the well-established longevity that is a prerequisite for such function, accumulating data argue for compromised