Multivariate Model of Associations between SGRQ-AS and Number of Acute Exacerbations and COPD-Related Hospitalizations Adjusting for FEV1 % Predicted and Prednisone for AE in Previous Year.*

FEV1 denotes forced expiratory volume in 1 second; AE acute exacerbation; ref reference group; and SGRQ-AS St. George's Respiratory Questionnaire Activity Score.*N = 168.§Rate ratios calculated for a MCID of 4 units for SGRQ-AS. The regression coefficients (SE) in natural log risk per 4-unit decrease in SGRQ-AS predicting AEs and COPD-related hospitalizations are 0.0484 (0.0202) and 0.0923 (0.0347), respectively.