The Antiviral Small-Interfering RNA Pathway Induces Zika Virus Resistance in Transgenic Aedes aegypti
收藏NIAID Data Ecosystem2026-03-12 收录
下载链接:
https://www.ncbi.nlm.nih.gov/sra/SRP278820
下载链接
链接失效反馈官方服务:
资源简介:
We have generated transgenic Ae. aegypti that express a ZIKV-specific inverted repeat RNA intended to trigger the mosquito siRNA anti-viral immune pathway. To confirm that the transgene is expressed and processed, we performed small RNA sequencing on both Higgs White Eye (HWE) & anti-NS3/4A-ZIKV transgenic Ae. aegypti 24 hours post-bloodmeal Overall design: small RNA profiling of 15 midguts from HWE & transgenic anti-NS3/4A-ZIKV Ae. aegypti 24 hours post-bloodmeal
创建时间:
2020-11-26



