Multiple signatures of somatic mutations have been identified in human cancer genomes. To investigate whether mutational signatures continue to be generated, and if so their temporal patterns of activ
Recent studies on mutational signatures in cancer genomes identified specific patterns of mutations (namely, signatures 2 and 13), which appear in more than 50% of the cancer types and reflect pattern
Additional file 2: Table S2. List of 112 candidate APOBEC-associated hotspot mutations identified in other cancer types presenting relatively high APOBEC mutagenesis (a total of 3751 cervical, head an
Dendritic cells (DC) are antigen presenting cells controlling T cell activation. In human, the diversity, ontogeny and functional capabilities of DC subsets are not fully understood. Here, we identifi
Additional file 2: Table S2. List of 112 candidate APOBEC-associated hotspot mutations identified in other cancer types presenting relatively high APOBEC mutagenesis (a total of 3751 cervical, head an
