Test No. 487: In Vitro Mammalian Cell Micronucleus Test

Organisation for Economic Co-operation and Development2026-02-07 收录

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The in vitro micronucleus test is a genotoxicity test for the detection of micronuclei in the cytoplasm of interphase cells.

List of most expressed genes at 15°C and their corresponding FPKM values.

基因表达

毒性基因

Damselysin (Dly) toxin is highlighted in bold. FPKM values shown correspond to mean values of the three biological replicates.

NIAID Data Ecosystem50

Data from: High throughput functional genomics identifies modulators of TCE metabolite genotoxicity and candidate susceptibility genes

毒性基因

功能基因组学

Trichloroethylene (TCE), an industrial chemical and environmental contaminant, is a human carcinogen. Reactive metabolites are implicated in renal carcinogenesis associated with TCE exposure, yet the

DataONE2017-08-09 更新40

Table_7_Long-Read–Based de novo Genome Assembly and Comparative Genomics of the Wheat Leaf Rust Pathogen Puccinia triticina Identifies Candidates for Three Avirulence Genes.XLSX

植物病原基因组学

毒性基因

Leaf rust, caused by Puccinia triticina (Pt), is one of the most devastating diseases of wheat, affecting production in nearly all wheat-growing regions worldwide. Despite its economic importance, gen

NIAID Data Ecosystem40

Evaluation of cytotoxic and genotoxic activities in the bone marrow of mice treated with sulfonamide chalcone N-{4-[3-(4-nitrophenyl)prop-2-enoyl]phenyl}-benzenesulfonamide (CPN) based on MNPCE and PCE/NCE frequency.

药物毒理学

毒性基因

1 Negative control: dimethylsulfoxide (DMSO) 0.1 mL/10 g body weight (b.w.). 2 Positive control: mitomycin C (MMC) 4 mg/kg (80% LD50). All values are mean ± SD of five mice. 3 Statistical analysis: on

NIAID Data Ecosystem50

Integration of metabolic activation with a predictive toxicogenomics signature to classify genotoxic versus nongenotoxic chemicals in human TK6 cells [BaP 8hr]. Homo sapiens

毒性基因

转录组学

The use of integrated approaches in genetic toxicology, including the incorporation of gene expression data to determine the molecular pathways involved in the response, is becoming more common. In a

NIAID Data Ecosystem40

Test No. 487: In Vitro Mammalian Cell Micronucleus Test

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