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Copper(I)-Catalyzed Three Component Reaction of Sulfonyl Azide, Alkyne, and Nitrone Cycloaddition/Rearrangement Cascades: A Novel One-Step Synthesis of Imidazolidin-4-ones

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Figshare2016-02-22 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Copper_I_Catalyzed_Three_Component_Reaction_of_Sulfonyl_Azide_Alkyne_and_Nitrone_Cycloaddition_Rearrangement_Cascades_A_Novel_One_Step_Synthesis_of_Imidazolidin_4_ones/2589745
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资源简介:
A novel one-pot azide–alkyne/ketenimine–nitrone cycloaddition sequence that is induced by copper(I) and allows the transformation of sulfonyl azides, alkynes, and nitrones to highly substituted imidazolidin-4-ones is described. The corresponding heterogeneous version utilizing Cu(I)-modified zeolites as recyclable heterogeneous catalysts shows marginally improved yield and diastereoselectivity.
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2016-02-22
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