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Simulations of AUC ratios for polypharmacy scenarios of multiple weak inhibitors of common metabolic pathway

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Figshare2026-02-03 更新2026-04-28 收录
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Matlab code to create figures in manuscript entitled "Addressing a Common Misconception of Simple Additive and Cumulative Drug Inhibition: Multiple Weak Inhibitors of Common Metabolic Pathway Do Not Pose a Strong Interaction Risk!"https://doi.org/10.1002/jcph.70154Scotcher D, Ghosh A, Galetin A, Rostami-Hodjegan A. Addressing a Common Misconception of Simple Additive and Cumulative Drug Inhibition: Multiple Weak Inhibitors of Common Metabolic Pathway Do Not Pose a Strong Interaction Risk! J Clin Pharmacol. 2026 Feb;66(2):e70154. doi: 10.1002/jcph.70154.

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2026-02-03
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