Primary mucosal melanoma (MM), which arise from melanocytes located in mucosal membranes, frequently present late and have a poor prognosis; ~14% 5-year survival rate. MM makes up only ~1.4% of all me
This study was the first-known large-scale effort to uncover the mutational spectrum of head and neck cancers. We analyzed whole-exome sequence from 92 tumor-normal pairs and retained 74 of them for s
This study demonstrated that the integration of gene manipulation in metabolic engneered strain Clostridium tyrobutyricum PAK-Em and further evolutionary engineered Clostridium tyrobutyricumHyd-Em.
