The Tug1 locus is required for male fertility and comprised of DNA, RNA and Protein regulatory elements. The Tug1 locus is required for male fertility and comprised of DNA, RNA and Protein regulatory elements

We have sequenced mouse embryonic fibroblasts (MEFs) and 6 organs (testes, prostate, liver, heart, spleen, and eye) harvested from adult male wild type and Tug1 knockout (Tug1_tm1.1Vlcg) mice in a C57BL/6J/129S6 (N3-C57BL/6J, no Neo) background. Additional sequencing was done on the testes of a Tug1 rescue mouse, which contains a doxycycline inducible allele for Tug1 (tg(Tug1)) and CAGs-rtTA3 in the Tug1 knockout background (Tug1_tmn1.1Vlcg). Overall design: Comparison between wild type and Tug1 knockout (Tug1_tm1.1Vlcg) organs and primary cell transcriptomes. Additional comparisons of the transcriptomes of wildtype, knockout, and rescue testes.