Transcription factor GATA1 is dispensable for mast cell differentiation in adult mice

ChEBI2014-03-02 更新2026-07-21 收录

肥大细胞分化

转录因子功能验证

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Transcription factor GATA1 is dispensable for mast cell differentiation in adult mice

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2014-03-02

Identification of a FOXO3/IRF7 circuit that limits inflammatory sequelae of antiviral responses (expression)

先天免疫调控

转录因子功能验证

We have used an unbiased systems approach to predict that a member of the forkhead family of transcription factors, FOXO3, is a negative regulator of a subset of antiviral genes. This prediction was v

NIAID Data Ecosystem70

A test of the pioneer factor hypothesis using ectopic liver gene activation [CUTTag]. A test of the pioneer factor hypothesis using ectopic liver gene activation [CUTTag]

转录因子功能验证

CUT&Tag技术

The Pioneer Factor Hypothesis (PFH) states that pioneer factors (PFs) are a subclass of transcription factors (TFs) that bind to and open inaccessible sites and then recruit non-pioneer factors (nonPF

NIAID Data Ecosystem60

TET2 Regulates Mast Cell Differentiation and Proliferation through Catalytic and Non-catalytic Activities.. TET2 Regulates Mast Cell Differentiation and Proliferation through Catalytic and Non-catalytic Activities.

肥大细胞分化

TET2

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem40

STARR-seq based mutagenesis of transcription factor binding sites

转录因子功能验证

高通量报告基因检测

We performed a STARR-seq based, massively parallel reporter assay on reference genome and mutation-containing oligonucleotide sequences from regions associated with a large number of transcription fac

NIAID Data Ecosystem60

Single-cell transcriptional profiling of late mast cell differentiation in mouse. Single-cell transcriptional profiling of late mast cell differentiation in mouse

单细胞转录组学

肥大细胞分化

Single-cell RNA sequencing of Lin- c-Kit+ FcεRI+ cells from mouse peritoneum captured the late mast cell differentiation Overall design: We performed single-cell RNA-sequencing of 95 basophil-mast cel

NIAID Data Ecosystem50

Transcription factor GATA1 is dispensable for mast cell differentiation in adult mice

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