MS proteomic profile in FH vs. non-FH patients under PCSK9i treatment

Non-depleted and depleted plasma samples were loaded on the Evotip and processed based on the manufacturer recommendation and analyzed by LC-MS using Evosep LC system and TimsTof SCP mass spectrometer (Bruker Daltonics). The mass spectrometer has been operated in Data-Independent-Analysis (DIA) mode. Data has been processed by Peaks Studio 11 software and DIA-NN software. The raw data from the MS analysis is attached.