Group deposition of Chikungunya virus nsP3 macrodomain in complex with inhibitors from the READDI-AC AViDD center -- Crystal structure of Chikungunya virus nsP3 macrodomain in complex with RA-0188465-01 (CHIKV_MacB-x2188)

Group deposition of Chikungunya virus nsP3 macrodomain in complex with inhibitors from the READDI-AC AViDD center -- Crystal structure of Chikungunya virus nsP3 macrodomain in complex with RA-0188465-01 (CHIKV_MacB-x2188) Descriptor: 2-(2-oxopyridin-1(2H)-yl)ethyl 3-methyl-1H-pyrrolo[2,3-b]pyridine-5-carboxylate, CHLORIDE ION, DIMETHYL SULFOXIDE, ... Authors: Aschenbrenner, J.C, Fairhead, M, Godoy, A.S, Almahli, H, Balcomb, B.H, Capkin, E, Chandran, A.V, Chen, W, Golding, M, Koekemoer, L, Lithgo, R.M, Marples, P.G, Ni, X, Saleem, R.S.Z, Thompson, W, Tomlinson, C.W.E, Wild, C, Winokan, M, Xavier, M.-A.E, Todd, M.H, Fearon, D, von Delft, F. Deposit date: 2024-10-04 Release date: 2024-10-16 Last modified: 2026-02-18 Method: X-RAY DIFFRACTION (1.74 Å) Cite: Group deposition of Chikungunya virus nsP3 macrodomain in complex with inhibitors from the READDI-AC AViDD center To Be Published

本数据集为基孔肯雅病毒（Chikungunya virus）nsP3宏结构域（macrodomain）与READDI-AC AViDD中心来源抑制剂复合物的群体沉积数据，包含基孔肯雅病毒nsP3宏结构域与RA-0188465-01（CHIKV_MacB-x2188）结合的晶体结构。
描述项：2-(2-氧代吡啶-1(2H)-基)乙基3-甲基-1H-吡咯并[2,3-b]吡啶-5-羧酸酯、氯离子、二甲基亚砜等。
作者：Aschenbrenner, J.C.、Fairhead, M.、Godoy, A.S.、Almahli, H.、Balcomb, B.H.、Capkin, E.、Chandran, A.V.、Chen, W.、Golding, M.、Koekemoer, L.、Lithgo, R.M.、Marples, P.G.、Ni, X.、Saleem, R.S.Z.、Thompson, W.、Tomlinson, C.W.E.、Wild, C.、Winokan, M.、Xavier, M.-A.E.、Todd, M.H.、Fearon, D.、von Delft, F.。
沉积日期：2024-10-04；发布日期：2024-10-16；最后修改日期：2026-02-18。
实验方法：X射线衍射（分辨率1.74埃）。
引用说明：基孔肯雅病毒nsP3宏结构域与READDI-AC AViDD中心抑制剂复合物的群体沉积数据，待发表。