Expression profiles of long noncoding RNAs in type 2 diabetes mellitus rat associated with the progression of ischemia-reperfursion injury

The aim of this study was to analyze the expressions of long noncoding RNA in rat with type 2 diabetes mellitus complicated with acute myocardial ischemia reperfusion injury. Type 2 diabetic rats were induced by high calorie diet combined with streptozotocin. IRI rats models were established by the ligation and release of left anterior descending coronary artery. The expression levels of lncRNA and mRNA in myocardial tissues of rats were detected via high-throughput sequencing technology.