Illumina data from Mcm5[A7] mutants

NIAID Data Ecosystem2026-03-11 收录

DNA双链断裂修复

果蝇突变体研究

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP255214 数据链接链接失效反馈

官方服务：

资源简介：

Sequencing of flies homozygous for Mcm5[A7] with the goal of determining how double strand breaks are repaired.

创建时间：

2020-08-20

H2A.Z is required to initiate DNA repair to prevent premature aging. H2A.Z is required to initiate DNA repair to prevent premature aging

DNA双链断裂修复

肌肉衰老机制

Histone variants are key epigenetic players, but their functional and physiological roles remain poorly understood. Here, we show that depletion of the histone variant H2A.Z in mouse skeletal muscle c

NIAID Data Ecosystem90

Origin of large insertions (>45 bp) monitored in the repair of distant DSEs (CD4-3200bp) upon 53BP1 and/or CtIP depletion, in the GC92 cell line.

DNA双链断裂修复

大片段插入起源

Origin of large insertions (>45 bp) monitored in the repair of distant DSEs (CD4-3200bp) upon 53BP1 and/or CtIP depletion, in the GC92 cell line.

NIAID Data Ecosystem70

53BP1 cooperation with the REV7–shieldin complex underpins DNA structure-specific NHEJ

DNA双链断裂修复

免疫球蛋白类别转换重组

53BP1 governs a specialized, context-specific branch of the classical non-homologous end joining DNA double-strand break repair pathway. Mice lacking 53bp1 (also known as Trp53bp1) are immunodeficient

NIAID Data Ecosystem40

Human RECQ1 Interacts with Ku70/80 and Modulates DNA End-Joining of Double-Strand Breaks

DNA双链断裂修复

非同源末端连接

Genomic instability is a known precursor to cancer and aging. The RecQ helicases are a highly conserved family of DNA-unwinding enzymes that play key roles in maintaining genome stability in all livi

NIAID Data Ecosystem70

Homo sapiens Clone ends

DNA双链断裂修复

APOBEC3G

Impact of A3G on non-homologous end-joining (NHEJ) of double-strand break repair

NIAID Data Ecosystem60