Pclo

ENCODES a protein that exhibits calcium ion binding; calcium-dependent phospholipid binding; transcription corepressor binding; INVOLVED IN modulation of excitatory postsynaptic potential; positive regulation of synaptic vesicle recycling; presynaptic active zone assembly; ASSOCIATED WITH abnormal cerebellar glomerulus morphology; abnormal synaptic vesicle number; abnormal synaptic vesicle recycling; ASSOCIATED WITH CHARGE syndrome (ortholog); epilepsy (ortholog); genetic disease (ortholog); FOUND IN axon; cone cell pedicle; cytoskeleton of presynaptic active zone; INTERACTS WITH (+)-schisandrin B; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine

编码一种具有钙离子结合能力的蛋白质；钙依赖性磷脂结合；转录共抑制因子结合；参与调节兴奋性突触后电位；正调控突触囊泡循环；前突触活性区组装；与异常小脑小球形态、异常突触囊泡数量、异常突触囊泡循环相关；与CHARGE综合征（同源基因）；癫痫（同源基因）；遗传疾病（同源基因）相关；存在于轴突；锥体细胞柄；前突触活性区细胞骨架；与(+)-五味子素B；2,2',4,4'-四溴二苯醚；2,3,7,8-四氯二苯并-对-二噁英相互作用。