Transcriptomic analysis of Ralstonia solanacearum under phage selection

Here we tested whether phage efficacy is limited by the growth temperature, which could potentially affect the rate of phage resistance. We find that phage resistance evolves regardless of the temperature, leading to trade-offs with pathogen virulence. To evaluate changes in Ralstonia solanacearum gene expression in response to phage infection, we cocultured R. solanacearum with phage and done this transcriptomic analysis.