CD8+ T Cells Promote Maturation of Liver-Resident NK Cells via the CD70-CD27 axis
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE130110
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We discovered that LrNK cells exhibit a relatively immature phenotype and impaired cytotoxic capacity in the absence of CD8+ T cells. The provision of CD8+ T cells to Cd8-/- or Rag1-/- mice led to the restoration of LrNK cell maturation LrNK and cNK mRNA profiles of wild type (WT) and CD8-/- mice were generated by deep sequencing, in triplicate, using Illumina
创建时间：
2019-07-22
