Global gene expression responses of Atlantic salmon skin to Moritella viscosa

Moritella viscosa is a Gram-negative pathogen that causes large, chronic ulcers, known as winter-ulcer disease, in the skin of several fish species including Atlantic salmon. However, the transcriptome response of Atlantic salmon to M. viscosa remained unknown before our study. We used a bath challenge approach and RNA-Seq analyses to profile the transcriptome responses of M. viscosa-infected Atlantic salmon skin at the lesion infection (Mv-At) and away from lesion (Mv-Aw) sites, compared to the non-infected control fish.