Effect of small molecules on activated astrocytes. Mus musculus
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA162319
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We have developed an assay to test the neuroprotective properties of compounds using stem cell–derived motor neurons and astrocytes, together with activated microglia as a stress paradigm. Hit compounds were discovered and the transcriptional response on activated astrocytes cells was tested. Overall design: Neural stem cell (NSC)-derived astrocytes (AC) were activated with LPS and IFN-γ and treated with hit compound for 4 hr.
创建时间：
2012-04-26
