fMRI of vesitibular migraine

From September 2023 to September 2024, 25 right-handed patients with VM and 17 patients with M were recruited from the Dizziness and Vertigo Outpatient Centre of the First Hospital of Harbin Medical University. All study subjects met the diagnostic criteria for VM according to the Headache Classification Committee of the International Headache Society (International Classification of Headache Disorders 3rd edition, ICHD-3); VM patients with concomitant neurological, psychiatric, auditory vestibular, or systemic diseases were excluded. MRI scans were performed on days 3-7 after a VM episode, and all patients were asked to be free of migraine and vertigo attacks on the day of the examination. All study subjects underwent routine neurological and neuro-otological examinations to rule out peripheral vestibular dysfunction. Demographic data were collected by face-to-face interviews with patients through standardised questionnaires. Headache patients were evaluated for migraine attacks using the HIT-6 score. Vertigo patients were evaluated for episodes of vestibular symptoms using the Dizziness Handicap Inventory (DHI scale) [24].
Recruitment of 5 age, gender, and education matched Hc group from the community, requiring no history of migraine, vestibular neuritis, Meniere's disease, secondary somatic vertigo, substance abuse, neurological, psychiatric, or systemic disorders, ischemic or hemorrhagic stroke, or severe head trauma involving any headache and dizziness. Volunteers with structural abnormalities on T1, lesions on T2, and moderate to severe white matter lesions on T2-FLAIR were excluded. This study was approved by the Ethics Committee of the First Hospital of Harbin Medical University. All participants voluntarily signed a written informed consent before entering the study.
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