Genome wide analysis of thoracic spinal cord at 5 days after T9 hemisection injury.

The goal of this study is to elucidate the influence of hemisection injury at thoracic spinal cord (T9) and epidural electrical spinal stimulation (L2-S1) on transcriptome of injured thoracic spinal cord. mRNA profiles of spinal cord at 5 days-post injury with or without epidural electrical spinal stimulation (L2-S1) and before injury were generated. Our study represents the detailed analysis of transcriptomes of injured spinal cord with biologic replicates, generated by RNA-seq technology.本研究旨在阐明胸脊髓（T9节段）半切损伤与硬膜外脊髓电刺激（L2-S1节段）对受损胸脊髓转录组的影响。我们通过RNA测序（RNA-seq）技术，生成了损伤前、损伤后5天伴或不伴该刺激的脊髓mRNA表达谱，并设置了生物学重复；本研究对上述受损脊髓的转录组开展了详细分析。