Apparent Kds (nM) for peptides binding to Mdm2/Mdm4 N-terminal domains and indicated variants.
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No significant variations are observed for binding of peptides to Mdm2-M62A (used in structural studies) compared to Mdm2. Values represent average ± SD (n = 2). Previously reported values are 34.35 ± 2.03 (*), 6.76 ± 2.11(**), 45.73 ± 7.65 (#) and 1360 ± 600 nM (##) [8].
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2017-12-12
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