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Overexpression of the FTO gene promotes the differentiation of the precursor adipocytes

NIAID Data Ecosystem2026-05-02 收录

牛前脂肪细胞分化

FTO基因

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP587766 数据链接链接失效反馈

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资源简介：

Investigating the effects of FTO , on differentiation of Guanling bovine preadipocytes in Guanling and molecular pathways.

应用场景：

创建时间：

2025-05-27

FTO基因

抗白血病药物发现

Fat mass obesity-associated protein (FTO) is a DNA/RNA demethylase involved in the epigenetic regulation of various genes and is considered a therapeutic target for obesity, cancer, and neurological d

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FTO deficiency reduces anxiety- and depression-like behaviors in mice via alterations in gut microbiota. Mus musculus

肠道微生物-情绪行为调控

FTO基因

Epidemiological evidence has identified robust associations between obesity and depression, demonstrating that obesity is a risk factor for future common mental disorders. In the present study, we inv

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The association of FTO gene SNP with obesity related parameters.

遗传关联分析

FTO基因

Notes M: male; F: female;After adjusting for multiple test, P>0.05.

Figshare2015-12-02 更新20

Associations of child FTO at rs9939609 with child eating behaviour at 4 years (n = 1718).

摄食行为遗传学

FTO基因

Abbreviations: OR, odds ratio; 95%CI, 95% confidence interval; ref, reference. aThe ORs represent the increased risk of high scores on CEBQ subscales per FTO minor allele at rs9939609.

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Functional Genomic Analyses of Hep-G2 Cell Line after FTO knockdown

葡萄糖代谢

FTO基因

To explore the molecular mechanism underlying glucose regulation by hepatic FTO, we used the human hepatocyte Hep-G2 cell line as an experimental platform and analyzed transcriptome changes following

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Overexpression of the FTO gene promotes the differentiation of the precursor adipocytes

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