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Total Syntheses of (−)-Hibiscone C and Lysergine: A Cyclization/Fragmentation Strategy

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NIAID Data Ecosystem2026-03-10 收录
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The first asymmetric total synthesis of (−)-hibiscone C and a concise synthesis of ergot alkaloid lysergine are described. Both syntheses were achieved using the radical cyclization/fragmentation strategy. This cascade reaction enabled the application of the strained bicycle as a synthon for the synthesis of highly substituted decalins in an efficient and stereoselective manner.

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2017-01-20
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