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Dearomatization Strategy of β‑Enamino Ester: Construction of Indenoazepines via Tandem Michael Addition/Polycyclization

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https://figshare.com/articles/dataset/Dearomatization_Strategy_of_Enamino_Ester_Construction_of_Indenoazepines_via_Tandem_Michael_Addition_Polycyclization/2398867
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A dearomatization strategy of β-enamino esters was developed to construct indenoazepine derivatives. The oxidative dearomatization was combined with a base-promoted tandem Michael addition/polycyclization and an acid-catalyzed aromatization. The nonaromatic structure of the Michael adducts might be essential to the realization of the 7-endo-dig cyclization.
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2013-07-05
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