Dissecting the Overlaps. Evaluation of the Relationships Between Neurological Soft Signs, Schizotypy and Interoceptive Awareness in Obsessive Compulsive Disorder.

Obsessive Compulsive Disorder's (OCD) etiology remains unknown. Identifying the relationships between neurological noft signs (NSSs), schizotypy, and interoceptive awareness may be helpful to clarify the neurodevelopment of OCD. In this cross-sectional study; relations between neurological soft signs, schizotypal traits and interoceptive awareness was evaluated. Between April 2023 and August 2023, thirty participants who applied to the Psychiatry Outpatient and Inpatient Clinics of Gazi University, Department of Psychiatry and diagnosed as obsessive compulsive disorder were included in this study. Thirty healthy subjects without any psychiatric or neurological diseases were included in as the control group. All the participants were required to fill out sociodemographic information form, Schizotypal Personality Questionnaire (SPQ), Multidimensional Assessment of Interoceptive Awareness-2 (MAIA-2), Hospital Anxiety and Depression Scale (HADS) and Yale Brown Obsessive Compulsive Scale (Y-BOCS). All subjects were examined for neurological soft signs by using the Neurological Evaluation Scale (NES). There was no significant difference between the groups in terms of age, gender, hand, foot, and eye preferences, and cerebral dominance. In the patient group analysis, there was a negative correlation between MAIA-2-Not Distracting subscale and NES-Sensorimotor Integration and NES-Other subscales; MAIA-2-Noticing subscale and SPQ-Interpersonal Schizotypy and SPQ-Disorganized Schizotypy sub-dimensions; MAIA-2-Trusting subscale and all SPQ sub-dimensions. It was thought that the study results could contribute to the understanding of the neurodevelopmental aspects of OCD.