Molecular diagnosis of rejection is emerging in kidney, heart, and lung transplant biopsies and could offer insights for liver transplant biopsies. Groups differed in median time post-transplant e.g.

NIAID Data Ecosystem60

single-cell RNA-seq data of human B cells in rejecting renal allograft and tonsil biopsies.. single-cell RNA-seq data of human B cells in rejecting renal allograft and tonsil biopsies.

单细胞RNA测序

移植排斥反应

Characterization of gene expression signature of intrarenal B cells in comparison with tonsil GC B cells. Overall design: Eight renal and seven tonsil samples collected in two cohorts. Samples of each

NIAID Data Ecosystem30

C3 SNPs and outcome after lung transplantation

移植排斥反应

补体基因多态性分析

Background: Development of chronic rejection is still a severe problem and causes high mortality rates after lung transplantation (LTx). Complement activation is important in the development of acute

NIAID Data Ecosystem70

The Multicopper Ferroxidase Hephaestin Enhances Intestinal Iron Absorption in Mice

铁代谢调控

基因敲除模型

Hephaestin is a vertebrate multicopper ferroxidase important for the transfer of dietary iron from intestinal cells to the blood. Hephaestin is mutated in the sex-linked anemia mouse, resulting in iro

NIAID Data Ecosystem50