Group analysis for right finger tapping: site of maximum activation for each ROI in controls and in patients before and during entacapone treatment.

Talairach x,y,z coordinates and peak T-scores are shown. SMA, supplementary motor area; M1, primary motor cortex; LPM, lateral premotor cortex. *for each ROI, the 2-way T-test resulted statistically different between PD patients at baseline and controls (p<0.05). #for each ROI, the 2-way T-test did not result statistically different between PD patients during entacapone and controls (p>0.05). °for each ROI, the 2-way T-test resulted statistically different between PD patients during entacapone and controls (p<0.05).