breast cancer

The current work obtained the approval of the Medical Ethics Committee of Zhongshan Hospital Affiliated with Dalian University. We obtained 230 pairs of postoperative pathological samples of patients undergoing breast cancer stored in paraffin wax blocks. These patients were admitted to the Department of Surgery of Zhongshan Hospital Affiliated with Dalian University between January 2014 and January 2018. All of the selected patients were naive to preoperative treatments, including neoadjuvant, radiotherapy, or chemotherapy. The selected patients had complete clinicopathological and follow-up information. All samples were subjected to freezing using liquid nitrogen (−80 °C). The present study was performed following the Declaration of Helsinki. The informed consent was acquired from all the patients.

本研究已获得大连大学附属中山医院医学伦理委员会的批准。我们收集了230对存储于石蜡块中的乳腺癌术后病理样本。这些患者于2014年1月至2018年1月期间被收入大连大学附属中山医院外科。所有入选患者均未接受过术前治疗，包括新辅助治疗、放疗或化疗。所选患者具备完整的临床病理学和随访信息。所有样本均经过液氮（-80°C）冷冻处理。本研究遵循《赫尔辛基宣言》的规定执行。所有患者均已获得知情同意。