Summary of predictors of positive treatment response identified in four RCTs.

Figshare2025-09-26 更新2026-04-28 收录

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Summary of predictors of positive treatment response identified in four RCTs.

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2025-09-26

Mouse ovarian cancer models recapitulate the human tumor microenvironment and patient response to treatment. Mouse ovarian cancer models recapitulate the human tumor microenvironment and patient response to treatment

癌微环境

治疗反应预测

Although there are many prospective targets in the tumor microenvironment (TME) of high-grade serous ovarian cancer (HGSOC), pre-clinical testing is challenging especially as there is limited informat

NIAID Data Ecosystem50

Supplementary Table 1 from Clinical Context Shapes the Relationship between Genomic Alterations and Response to AR Inhibitors and Chemotherapy in Metastatic Prostate Cancer

前列腺癌基因组

治疗反应预测

Supplementary Table 1. This table contains the genes comprising the pathway gene signature used to evaluate genetic alterations in prostate cancer specimens.

Figshare2025-07-01 更新30

Table_1_Development and validation of an inflammatory response-related signature in triple negative breast cancer for predicting prognosis and immunotherapy.xls

三阴性乳腺癌预后

治疗反应预测

BackgroundInflammation is one of the most important characteristics of tumor tissue. Signatures based on inflammatory response-related genes (IRGs) can predict prognosis and treatment response in a va

NIAID Data Ecosystem30

CCNE1 copy-number is a biomarker for response to combination WEE1-ATR inhibition in ovarian and endometrial cancer models

肿瘤生物标志物

治疗反应预测

CCNE1 copy number was identified as a biomarker for the combination inhibition of WEE1 and ATR therapy. Multiple patient-derived xenograph (PDX) were generated and genomic sequenced to get the mutatio

NIAID Data Ecosystem30

Exhausted intratumoral Vδ2- γδ T cells in human kidney cancer retain effector function [scRNA-seq]. Exhausted intratumoral Vδ2- γδ T cells in human kidney cancer retain effector function [scRNA-seq]

肿瘤免疫微环境

治疗反应预测

Gamma delta (γδ) T cells reside within human tissues including tumors, but their role in mediating anti-tumor response with immune checkpoint inhibition is unknown. Using single-cell approaches, we fo

NIAID Data Ecosystem30

Summary of predictors of positive treatment response identified in four RCTs.

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