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Leptin-mediated control of body weight by a conserved population of Glp1r-expressing neurons

NIAID Data Ecosystem2026-03-13 收录

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体重调控神经机制

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE172463 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2021-12-14

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能量代谢调控

Leptin is a hormone that regulates a variety of physiological processes. To investigate into the role of leptin in body mass in high-fat-fed animals. Male striped field mice ( Apodemus agrarius )

DataCite Commons2025-02-12 更新750

32 mitochondrial genes involved in leptin signaling.

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病毒基因表达调控

aFC_SQ: fold change in gene expression after peripheral (subcutaneous) leptin administration as compared to vehicle subcutaneous treatment. bFC_ICV: fold change in gene expression after central (intra

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Defining the Transcriptional Targets of Leptin Reveals a Role for Atf3 in Leptin Action

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神经元转录调控

We employed translating ribosome affinity purification followed by RNA sequencing to isolate and analyze mRNA from the hypothalamic LepRb neurons of wild-type or leptin-deficient (Lepob/ob) mice treat

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Correlations between cortical bone parameters, serum total leptin and sOB-R levels with and without age and BMI adjustment.

骨代谢

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*correlation with p-value <0.05, **correlation with p-value <0.01, #statistically significant after Hochberg-Benjamini correction for multiple comparison. Abbreviations: AIS, adolescent idiopathic sco

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Common genes altered by relaxin.

基因表达调控

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Common genes altered by relaxin.

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