The stress response factors Yap6, Cin5, Phd1, and Skn7 direct targeting of the conserved co-repressor Tup1-Ssn6

The budding yeast transcriptional corepressor Tup1-Ssn6 is a model for studying similar repressosome complexes in multicellular eukaryotes出芽酵母（budding yeast）的转录共阻遏物Tup1-Ssn6，是研究多细胞真核生物中类似阻遏体复合物（repressosome）的经典模型。