Additional file 4: Table S3. Statistical enrichment of GWAS loci in CTCF peaks. Χ2 distribution with 1 degree of freedom used to calculate P values indicating the probability of observing a difference
Loci were defined by the set of all SNPs in LD (r2 > 0.6, 1000 Genomes Phase 3 European samples) with an independently significant SNP (p < 5e-8) at that locus. Start and end refer to the left- and ri
OR represents the odds ratio per copy of risk allele (A). P-values were calculated using a logistic regression analysis with additive model (adjusted for sex, age, log-transformed body mass index and
This dataset contains supplemental material as part of a PhD thesis: Identification of Shared Genetic Risk Loci between Hypertensive Disorders of Pregnancy and Later-Life Cardiovascular Disease. The m
Excess thyroid hormones have complex metabolic effects, particularly hyperthyroidism, and are associated with various cardiovascular risk factors. Previous candidate gene studies have indicated that g