Crystal structure of human D-2-hydroxyglutarate dehydrogenase in complex with D-2-hydroxyglutarate (D-2-HG)

Crystal structure of human D-2-hydroxyglutarate dehydrogenase in complex with D-2-hydroxyglutarate (D-2-HG) Descriptor: (2R)-2-hydroxypentanedioic acid, D-2-hydroxyglutarate dehydrogenase, mitochondrial, ... Authors: Yang, J, Zhu, H, Ding, J. Deposit date: 2020-01-12 Release date: 2021-01-13 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Structure, substrate specificity, and catalytic mechanism of human D-2-HGDH and insights into pathogenicity of disease-associated mutations. Cell Discov, 7, 2021人类D-2-羟戊二酸脱氢酶（D-2-hydroxyglutarate dehydrogenase）与D-2-羟戊二酸（D-2-hydroxyglutarate，D-2-HG）的复合物晶体结构 描述项：(2R)-2-羟基戊二酸、线粒体D-2-羟戊二酸脱氢酶…… 作者：Yang J、Zhu H、Ding J 提交日期：2020-01-12 发布日期：2021-01-13 最后修改日期：2023-11-29 实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率2.65埃（Å） 引用文献：《人类D-2-HGDH的结构、底物特异性与催化机制及疾病相关突变的致病机制研究》，Cell Discovery，2021年，第7卷