Bos taurus pangenome graph

The output file of hierarchical alignment (hal) of 14 Bos taurus genomes, including the Hanwoo assembly, was generated using the Minigraph-Cactus Pangenome Pipeline. 14 assemblies were collected with the Hereford assembly, ARS-UCD1.3, as the reference genome. 8 haplotype-resolved assemblies of Angus (UOA_Angus_1, GCF_002263795.3), Brahman (UOA_Brahman_1), Simmental (ARS-Simm1.0), Scottish Highland bull (ARS_UNL_Btau-highland_paternal_1.0_alt, GCA_009493655.1), N’Dama (ROSLIN_BTT_NDA1), Ankole (ROSLIN_BTI_ANK1), Jersey (ARS-LIC_NZ_Jersey, GCA_021234555.1), Holstein Friesian (ARS-LIC_NZ_Holstein-Friesian_1, GCA_021347905.1) Original Braunvieh, Nellore, Brown Swiss, and Piedmontese were collected from the public database (https://doi.org/10.5281/ZENODO.5906579) and scaffolded and merged by RagTag8 following the protocol of previous article. <br> This hal file was generated using Minigraph-Cactus pangenome pipeline.

本数据集包含14个普通牛（Bos taurus）基因组的层级比对（hierarchical alignment, HAL）输出文件，其中涵盖韩牛组装结果，该文件通过Minigraph-Cactus泛基因组管线生成。本次纳入的14个基因组组装体以赫里福德组装体ARS-UCD1.3作为参考基因组进行收集，其中8个为单倍型解析组装体，分别为安格斯牛（UOA_Angus_1, GCF_002263795.3）、婆罗门牛（UOA_Brahman_1）、西门塔尔牛（ARS-Simm1.0）、苏格兰高地公牛（ARS_UNL_Btau-highland_paternal_1.0_alt, GCA_009493655.1）、恩达马牛（ROSLIN_BTT_NDA1）、安科勒牛（ROSLIN_BTI_ANK1）、泽西牛（ARS-LIC_NZ_Jersey, GCA_021234555.1）以及荷斯坦弗里生牛（ARS-LIC_NZ_Holstein-Friesian_1, GCA_021347905.1）。原始布朗维耶牛、内洛尔牛、瑞士褐牛与皮埃蒙特牛则从公共数据库（https://doi.org/10.5281/ZENODO.5906579）获取，并按照既往文献的方案通过RagTag8完成基因组支架构建与合并操作。本HAL文件通过Minigraph-Cactus泛基因组管线生成。