We show that synthesising histones with different chemical modifications can induce a transcriptional response that alters the phenotype of those cells. Overall design: Examination of the effect of di
Histones can undergo many post-translational modifications that are involved in transcription regulation. This pathway provides an overview of various modifications for histones H3 and H4 and the enz
The modification of chromatin structure is important for a number of nuclear functions, exemplified by the regulation of transcription. This review discusses recent studies of covalent histone modific
