Sequencing of patient-derived xenograft (PDX) mouse models allows investigation of the molecular mechanisms of human tumor samples engrafted in a mouse host. Thus, both human and mouse genetic materia
Identification of new treatments for relapsing pediatric cancer is an unmet clinical need and a societal challenge. Liver cancer occurrence in infancy, 1.5 for million children per year, falls far bel
We have generated and comprehensively characterized 30 patient-derived orthotopic xenograft (PDOX) models and 7 cell lines represeneting subgroups of medulloblastoma, high-grade glioma, atypical terat
This dataset contains key characteristics about the data described in the Data Descriptor A multi-modal data resource for investigating topographic heterogeneity in patient-derived xenograft tumors.
Additional file 1: Fig. S1 Histological characteristics of primary tumors and paired PDX models. a. The histological features of cervical cancer primary tumors and corresponding PDX tumors were assess
