This study investigates the potential of a triple combination of meropenem, a novel metallo-beta-lactamase (MBL) inhibitor, InC58, and avibactam, a serine-beta-lactamase (SBL) inhibitor for a broad-sp

NIAID Data Ecosystem30

Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid and subsequent glycerol-boric acid-ester formation, 50 ms

β-内酰胺酶耐药机制

蛋白质时间分辨结构

Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid and subsequent glycerol-boric acid-ester formation, 50 ms

NIAID Data Ecosystem10

CTX-M-14 beta-lactamase mutant- N132A

β-内酰胺酶耐药机制

蛋白质晶体结构解析

CTX-M-14 beta-lactamase mutant- N132A Descriptor: Beta-lactamase, DI(HYDROXYETHYL)ETHER Authors: Lu, S, Neetu, N, Palzkill, T. Deposit date: 2022-09-23 Release date: 2023-04-05 Last modified: 2023-10-

Protein Data Bank Japan2023-10-25 更新50

The Structural Role of N170 in Substrate-assisted Deacylation in KPC-2 β-Lactamase

β-内酰胺酶耐药机制

分子动力学模拟

The dataset contains trajectories, structure files, HILLS files and COLVAR files for D179 WT, D179A, D179Q, D179N, D179Y, R164 WT, R164S, R164H

NIAID Data Ecosystem10