Crystal structure of human DNPH1 bound to inhibitor 1b
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Crystal structure of human DNPH1 bound to inhibitor 1b Descriptor: 1,2-ETHANEDIOL, 1-(2-deoxy-2-fluoro-5-O-phosphono-beta-D-arabinofuranosyl)-5-(hydroxymethyl)pyrimidine-2,4(1H,3H)-dione, 5-hydroxymethyl-dUMP N-hydrolase, ... Authors: Wagner, A.G, Schramm, V.L, Almo, S.C, Ghosh, A. Deposit date: 2024-08-21 Release date: 2025-02-05 Last modified: 2025-02-26 Method: X-RAY DIFFRACTION (1.13 Å) Cite: Transition State Analogs of Human DNPH1 Reveal Two Electrophile Migration Mechanisms. J.Med.Chem., 68, 2025
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2024-08-21
