Hydroxyapatite implants are widely used in orbital reconstruction due to their biocompatibility and capacity for osseointegration. Complications such as implant exposure or extrusion typically occur i
Here we demonstrate for the first time that AGEs adsorb and accumulate on implantable biomaterial surfaces, causing impaired inflammatory, fibrotic and osteogenic responses, revealing a previously unr
ABSTRACT We describe a case of late-onset remarkable depigmentation of a small aperture corneal inlay implanted for presbyopia compensation. The patient was a participant in a clinical trial designed