BackgroundInduction of Type I Interferon (IFN) genes constitutes an essential step leading to innate immune responses during virus infection. Sendai virus (SeV) infection of B lymphoid Namalwa cells t
aCalculations were as followed: for each mouse, the ratio between type III and type I IFN transcripts (IFN-λ/IFN-α or IFN-λ/IFN-β was calculated for the liver and for the brain. Mean ratios were then
The cellular prion protein (PrPC) has been extensively studied because of its pivotal role in prion diseases; however, its functions remain incompletely understood. A unique line of goats has been ide
S1I Fig. Viral gene expression heterogeneity does not completely explain IFN-β expression. BC3-IFN-βp-tdTomato reporter cells were treated with 20 ng/ml TPA for 48 hours to induce the lytic cycle (“ly